| 名称 |
anti- IL-6 antibody |
| 来源 |
Mouse |
| 应用 |
ELISA, IHC, WB |
| 反应 |
Human, Rat |
| 稀释范围 |
WB: 1:500-1:5000; IHC: 1:20-1:200 |
| 克隆 |
monoclonal |
| 蛋白号 |
P05231 |
| 纯化 |
Protein A+G purification |
| 纯度 |
≥95% as determined by SDS-PAGE |
| 状态 |
liquid |
| 免疫原 |
interleukin 6(interferon, beta 2) |
| 亚型 |
IgG2a |
| 基因ID |
6D11 |
| 存储 |
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| 别名 |
B cell stimulatory factor 2, BSF 2, BSF2, CDF, CTL differentiation factor, HGF, HSF, Hybridoma growth factor, IFN beta 2, IFNB2, IL 6, IL6, IL-6, Interferon beta 2, Interleukin 6 |
| 背景介绍 |
Interleukin-6(IL-6) is an interleukin that acts as both a pro-inflammatory and anti-inflammatory cytokine. IL-6 protein is secreted by a variety of cell types including T cells and macrophages as phosphorylated and variably glycosylated molecule. IL-6 Plays an essential role in the final differentiation of B-cells into Ig-secreting cells involved in lymphocyte and monocyte differentiation. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. IL-6 is also considered a myokine, a cytokine produced from muscle, and is elevated in response to muscle contraction. IL-6 has been shown to interact with interleukin-6 receptor and glycoprotein 130. Additionally, IL-6 is involved in hematopoiesis, bone metabolism, and cancer progression, and has been defined an essential role in directing transition from innate to acquired immunity. |
