| 名称 |
anti- Cardiac Troponin I antibody |
| 来源 |
Rabbit |
| 应用 |
ELISA, WB, IHC |
| 反应 |
Human, Mouse, Rat |
| 稀释范围 |
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200 |
| 克隆 |
polyclonal |
| 蛋白号 |
P19429 |
| 分子质量 |
26 kDa |
| 纯化 |
Immunogen affinity purified |
| 纯度 |
≥95% as determined by SDS-PAGE |
| 状态 |
liquid |
| 免疫原 |
troponin I type 3 (cardiac) |
| 亚型 |
IgG |
| 存储 |
PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.) |
| 别名 |
Cardiac troponin I, cTnI, RCM1, TNNC1, TNNI3, troponin I type 3 (cardiac), Troponin I, cardiac muscle |
| 背景介绍 |
Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). |
