5α-Androstan-3β-ol

产品编号 HY-19330
产品分类 抑制剂
CAS号 1224-92-6
分子式 C19H32O
分子量 276.50
品牌 华韵生物
规格 5mg 10mg 50mg
应用 5α-Androstan-3β-ol is a steroidal androgen.It binds to the androgen receptor in a cell-free assay (IC50 = 1.7 µM) and activates the pregnane X receptor (PXR) in HepG2 cells in a reporter assay (EC50 = 0.8 µM). 5α-Androstan-3β-ol also inhibits the androst-4-ene-3,17-dione hydroxylase activities of 16α- and 6β-hydroxylase but not 16β- or 7α-hydroxylase (IC50s = 70, 110, >150, and >150 µM, respectively). It decreases testis weight and sperm production in mice when administered at a dose of 30 mg/kg.
品牌 货号 纯度 规格 目录价(CNY) 会员价(CNY) 数量 购物车
华韵生物 HY-19330-5mg 5mg ¥995.00
华韵生物 HY-19330-10mg 10mg ¥1887.00
华韵生物 HY-19330-50mg 50mg ¥4972.00
COA查询 查询MSDS 大包装询盘
CAS号 1224-92-6
分子式 C19H32O
分子量 276.50
纯度 ≥98%
状态 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至37℃，然后在超声波浴中震荡一段时间。
存储 Pure form：
-20°C，3 years / 4°C，2 years ;
In solvent：
-80°C，6 months / -20°C，1 month ;
背景介绍 5α-Androstan-3β-ol is a steroidal androgen.It binds to the androgen receptor in a cell-free assay (IC50 = 1.7 µM) and activates the pregnane X receptor (PXR) in HepG2 cells in a reporter assay (EC50 = 0.8 µM). 5α-Androstan-3β-ol also inhibits the androst-4-ene-3,17-dione hydroxylase activities of 16α- and 6β-hydroxylase but not 16β- or 7α-hydroxylase (IC50s = 70, 110, >150, and >150 µM, respectively). It decreases testis weight and sperm production in mice when administered at a dose of 30 mg/kg.
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