4-oxo Isotretinoin
| 产品编号 | HY-19328 |
| 产品分类 | 抑制剂 |
| CAS号 | 71748-58-8 |
| 分子式 | C20H26O3 |
| 分子量 | 314.40 |
| 品牌 | 华韵生物 |
| 规格 | 5mg 10mg 25mg |
| 应用 | 4-oxo Isotretinoin is an active metabolite of the retinoid isotretinoin . It is formed from isotretinoin by several cytochrome P450 (CYP450) isoforms, including CYP3A, CYP2B6, and CYP2C19. 4-oxo Isotretinoin (10 µM) increases protein expression of cytokeratin 7 (CK7) and CK19 in normal human epidermal keratinocytes. It inhibits proliferation of retinoid-sensitive UM-SCC-22A and UM-SCC-35 head and neck squamous cell carcinoma (HNSCC) cells in a concentration-dependent manner.4-oxo Isotretinoin has been found in influent and effluent wastewater. It is teratogenic to mouse embryos when administered to pregnant dams at a dose of 100mg/kg on day 11 of gestation. |
| 品牌 | 货号 | 纯度 | 规格 | 目录价(CNY) | 会员价(CNY) | 数量 | 购物车 |
|---|---|---|---|---|---|---|---|
| 华韵生物 | HY-19328-5mg | 5mg | ¥2925.00 |
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| 华韵生物 | HY-19328-10mg | 10mg | ¥5557.00 |
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| 华韵生物 | HY-19328-25mg | 25mg | ¥12445.00 |
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