2-Amino-3,8-dimethylimidazo-[4,5-f]-quinoxaline

产品编号 HY-19322
产品分类 抑制剂
CAS号 77500-04-0
分子式 C11H11N5
分子量 213.20
品牌 华韵生物
规格 5mg 10mg 25mg
应用 2-Amino-3,8-dimethylimidazo-[4,5-f]-quinoxaline (MeIQx) is a food-derived carcinogen that has been found in high temperature-cooked fish and meats. It is activated by hydroxylation and subsequent O-acetylation via the cytochrome P450 (CYP) isoform CYP1A2 and N-acetyltransferase 2, respectively, in UV5 cells expressing the human enzymes to a metabolite that reacts with DNA to form adducts.MeIQx (200 and 400 ppm in the diet) induces tumor formation in rats.
品牌 货号 纯度 规格 目录价(CNY) 会员价(CNY) 数量 购物车
华韵生物 HY-19322-5mg 5mg ¥2037.00
华韵生物 HY-19322-10mg 10mg ¥3890.00
华韵生物 HY-19322-25mg 25mg ¥8667.00
CAS号 77500-04-0
分子式 C11H11N5
分子量 213.20
纯度 ≥95%
状态 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。
储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
为了提高溶解度,请将管子加热至37℃,然后在超声波浴中震荡一段时间。
存储 Pure form:
-20°C,3 years / 4°C,2 years ;
In solvent:
-80°C,6 months / -20°C,1 month ;
背景介绍 2-Amino-3,8-dimethylimidazo-[4,5-f]-quinoxaline (MeIQx) is a food-derived carcinogen that has been found in high temperature-cooked fish and meats. It is activated by hydroxylation and subsequent O-acetylation via the cytochrome P450 (CYP) isoform CYP1A2 and N-acetyltransferase 2, respectively, in UV5 cells expressing the human enzymes to a metabolite that reacts with DNA to form adducts.MeIQx (200 and 400 ppm in the diet) induces tumor formation in rats.
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