WD2000-012547

产品编号 HY-19313
产品分类 抑制剂
CAS号 283172-68-9
分子式 C17H14N2O
分子量 262.31
品牌 华韵生物
规格 1mg 5mg 10mg 20mg
应用 WD2000-012547 is a selective poly(ADP-ribose)-polymerase (PARP-1) inhibitor with a pKi of 8.221. Poly(ADP-ribose) polymerase-1 (PARP-1) functions as a DNA damage sensor and signaling molecule. It plays a vital role in the repair of DNA strand breaks induced by radiation and chemotherapeutic drugs; inhibitors of this enzyme have the potential to improve cancer chemotherapy or radiotherapy. WD2000-012547 (Compound 66) is a representative PARP-1 inhibitor with a pKi of 8.221.
品牌 货号 纯度 规格 目录价(CNY) 会员价(CNY) 数量 购物车
华韵生物 HY-19313-1mg 1mg ¥22305.00
华韵生物 HY-19313-5mg 5mg ¥44390.00
华韵生物 HY-19313-10mg 10mg ¥75437.00
华韵生物 HY-19313-20mg 20mg ¥133165.00
COA查询 查询MSDS 大包装询盘
CAS号 283172-68-9
分子式 C17H14N2O
分子量 262.31
纯度 ≥98%
状态 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至37℃，然后在超声波浴中震荡一段时间。
存储 Pure form：
-20°C，3 years / 4°C，2 years ;
In solvent：
-80°C，6 months / -20°C，1 month ;
背景介绍 WD2000-012547 is a selective poly(ADP-ribose)-polymerase (PARP-1) inhibitor with a pKi of 8.221. Poly(ADP-ribose) polymerase-1 (PARP-1) functions as a DNA damage sensor and signaling molecule. It plays a vital role in the repair of DNA strand breaks induced by radiation and chemotherapeutic drugs; inhibitors of this enzyme have the potential to improve cancer chemotherapy or radiotherapy. WD2000-012547 (Compound 66) is a representative PARP-1 inhibitor with a pKi of 8.221.
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