Aspulvinone O

产品编号 HY-18481
产品分类 抑制剂
CAS号 914071-54-8
分子式 C27H28O6
分子量 448.51
品牌 华韵生物
规格 1mg 5mg
应用 Aspulvinone O is a fungal metabolite that has been found in P. variotti and has antioxidant and anticancer activities. It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; ) radicals in a cell-free assay (IC = 11.6 µM). Aspulvinone O inhibits aspartate transaminase 1 (GOT1; K = 3.32 µM) and is cytotoxic to PANC-1, AsPC-1, and SW1990 pancreatic cancer cells (ICs = 20.54-26.8 µM). It reduces the oxygen consumption rate (OCR) and induces apoptosis in SW1990 cells. Aspulvinone O (2.5 and 5mg/kg) reduces tumor growth in an SW1990 mouse xenograft model.
品牌 货号 纯度 规格 目录价(CNY) 会员价(CNY) 数量 购物车
华韵生物 HY-18481-1mg 1mg ¥15671.00
华韵生物 HY-18481-5mg 5mg ¥62685.00
COA查询 查询MSDS 大包装询盘
CAS号 914071-54-8
分子式 C27H28O6
分子量 448.51
纯度 ≥95%
状态 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至37℃，然后在超声波浴中震荡一段时间。
存储 Pure form：
-20°C，3 years / 4°C，2 years ;
In solvent：
-80°C，6 months / -20°C，1 month ;
背景介绍 Aspulvinone O is a fungal metabolite that has been found in P. variotti and has antioxidant and anticancer activities. It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; ) radicals in a cell-free assay (IC = 11.6 µM). Aspulvinone O inhibits aspartate transaminase 1 (GOT1; K = 3.32 µM) and is cytotoxic to PANC-1, AsPC-1, and SW1990 pancreatic cancer cells (ICs = 20.54-26.8 µM). It reduces the oxygen consumption rate (OCR) and induces apoptosis in SW1990 cells. Aspulvinone O (2.5 and 5mg/kg) reduces tumor growth in an SW1990 mouse xenograft model.
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