5-trans Latanoprost

产品编号 HY-18478
产品分类 抑制剂
CAS号 913258-34-1
分子式 C26H40O5
分子量 432.60
品牌 华韵生物
规格 1mg 5mg 10mg 50mg
应用 Latanoprost is an F-series prostaglandin analog which has been approved for use as an ocular hypotensive drug. 5-trans Latanoprost is an isomer of latanoprost wherein the double bond between carbons 5 and 6 has been changed from cis (Z) to trans (E). The trans isomer of latanoprost occurs as an impurity of between 2-5% in most commercial preparations of the bulk drug product. The present compound was prepared primarily as an analytical standard for detection and quantitation of this impurity. From what can be inferred from the study of other trans isomers of F-type prostaglandins, 5-trans latanoprost’s biological activity is likely to be similar to that of the cis isomer. However, there are no specific published reports on the biological activity, and on the intraocular hypotensive activity in particular, of 5-trans latanoprost.
品牌 货号 纯度 规格 目录价(CNY) 会员价(CNY) 数量 购物车
华韵生物 HY-18478-1mg 1mg ¥4646.00
华韵生物 HY-18478-5mg 5mg ¥20947.00
华韵生物 HY-18478-10mg 10mg ¥37170.00
华韵生物 HY-18478-50mg 50mg ¥116156.00
CAS号 913258-34-1
分子式 C26H40O5
分子量 432.60
纯度 ≥98%
状态 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。
储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
为了提高溶解度,请将管子加热至37℃,然后在超声波浴中震荡一段时间。
存储 Pure form:
-20°C,3 years / 4°C,2 years ;
In solvent:
-80°C,6 months / -20°C,1 month ;
背景介绍 Latanoprost is an F-series prostaglandin analog which has been approved for use as an ocular hypotensive drug. 5-trans Latanoprost is an isomer of latanoprost wherein the double bond between carbons 5 and 6 has been changed from cis (Z) to trans (E). The trans isomer of latanoprost occurs as an impurity of between 2-5% in most commercial preparations of the bulk drug product. The present compound was prepared primarily as an analytical standard for detection and quantitation of this impurity. From what can be inferred from the study of other trans isomers of F-type prostaglandins, 5-trans latanoprost’s biological activity is likely to be similar to that of the cis isomer. However, there are no specific published reports on the biological activity, and on the intraocular hypotensive activity in particular, of 5-trans latanoprost.
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