Noscapine (hydrochloride)

产品编号 HY-18473
产品分类 抑制剂
CAS号 912-60-7
分子式 C22H23NO7.HCl
分子量 413.44
品牌 华韵生物
规格 500mg 1g 5g
应用 Noscapine is an alkaloid that has been found in opium and has anticancer and antitussive properties. It binds to tubulin and induces cell cycle arrest at the G/M phase in HeLa cells when used at a concentration of 20 µM. Noscapine induces apoptosis in HeLa cells and thymocytes (ICs = 25 and 10 µM, respectively) and reduces proliferation of MCF-7 breast and Renal 1983 bladder cancer cells (ICs = 42.3 and 39.1 µM, respectively). In vivo, noscapine (120 mg/kg) induces tumor regression in an MCF-7 mouse xenograft model. Noscapine (30 and 70 mg/kg) decreases the number of citric acid-induced coughs in guinea pigs.
品牌 货号 纯度 规格 目录价(CNY) 会员价(CNY) 数量 购物车
华韵生物 HY-18473-500mg 500mg ¥2283.00
华韵生物 HY-18473-1g 1g ¥3465.00
华韵生物 HY-18473-5g 5g ¥13702.00
COA查询 查询MSDS 大包装询盘
CAS号 912-60-7
分子式 C22H23NO7.HCl
分子量 413.44
纯度 ≥98%
状态 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至37℃，然后在超声波浴中震荡一段时间。
存储 Pure form：
-20°C，3 years / 4°C，2 years ;
In solvent：
-80°C，6 months / -20°C，1 month ;
背景介绍 Noscapine is an alkaloid that has been found in opium and has anticancer and antitussive properties. It binds to tubulin and induces cell cycle arrest at the G/M phase in HeLa cells when used at a concentration of 20 µM. Noscapine induces apoptosis in HeLa cells and thymocytes (ICs = 25 and 10 µM, respectively) and reduces proliferation of MCF-7 breast and Renal 1983 bladder cancer cells (ICs = 42.3 and 39.1 µM, respectively). In vivo, noscapine (120 mg/kg) induces tumor regression in an MCF-7 mouse xenograft model. Noscapine (30 and 70 mg/kg) decreases the number of citric acid-induced coughs in guinea pigs.
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