R-(?)-α-Methylhistamine (hydrochloride)
| 产品编号 | HY-17884 |
| 产品分类 | 抑制剂 |
| CAS号 | 75614-89-0 |
| 分子式 | C6H11N3.2HCl |
| 分子量 | 125.17 |
| 品牌 | 华韵生物 |
| 规格 | 1mg 5mg 10mg 25mg |
| 应用 | R-(−)-α-Methylhistamine is a histamine H receptor agonist with diverse biological activities. It inhibits the release of histamine induced by antidromic electrical stimulation of the sciatic nerve in rats when administered at doses ranging from 0.25 to 2mg/kg, an effect that can be reversed by the selective histamine H receptor antagonist thioperamide . R-(−)-α-Methylhistamine (0.5-50 nmol) inhibits gastric acid secretion in rats when administered intracerebroventricularly but not intravenously. It reduces isolation-induced vocalizations and aggressive behavior in a resident-intruder test in guinea pig pups and mice, respectively. R-(−)-α-Methylhistamine (30 mg/kg) decreases freezing time in a conditioned fear stress test in rats. It also acts synergistically with fentanyl to reduce nociception and plasma extravasation in a mouse model of chronic inflammation induced by complete Freund's adjuvant. |
| 品牌 | 货号 | 纯度 | 规格 | 目录价(CNY) | 会员价(CNY) | 数量 | 购物车 |
|---|---|---|---|---|---|---|---|
| 华韵生物 | HY-17884-1mg | 1mg | ¥1968.00 |
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| 华韵生物 | HY-17884-5mg | 5mg | ¥7402.00 |
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| 华韵生物 | HY-17884-10mg | 10mg | ¥13781.00 |
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| 华韵生物 | HY-17884-25mg | 25mg | ¥29531.00 |
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