Sumatriptan-d6 (succinate)

产品编号 HY-14017
产品分类 抑制剂
CAS号 1397195-80-0
分子式 C14H15D6N3O2S.1/2C4H6O4
分子量 301.44
品牌 华韵生物
规格 1mg
应用 Sumatriptan-d is intended for use as an internal standard for the quantification of sumatriptan by GC- or LC-MS. Sumatriptan is an agonist of the serotonin (5-HT) receptor subtypes 5-HT and 5-HT (ICs = 9.3 and 7.3 nM, respectively). It also binds to the 5-HT receptor (IC = 17.8 nM). It induces vasoconstriction in isolated human middle meningeal arteries (EC = 89.9 nM), an effect that can be reduced by the 5-HT receptor antagonists GR125743 and GR127935 . Sumatriptan reduces acute, but not chronic, mechanical hyperalgesia in a mouse model of pain induced by nitroglycerin, which is a known migraine trigger in humans. Formulations containing sumatriptan have been used in the treatment of migraine headache.
品牌 货号 纯度 规格 目录价(CNY) 会员价(CNY) 数量 购物车
华韵生物 HY-14017-1mg 1mg ¥24806.00
COA查询 查询MSDS 大包装询盘
CAS号 1397195-80-0
分子式 C14H15D6N3O2S.1/2C4H6O4
分子量 301.44
纯度 ≥99% deuterated forms (d1-d6)
状态 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至37℃，然后在超声波浴中震荡一段时间。
存储 Pure form：
-20°C，3 years / 4°C，2 years ;
In solvent：
-80°C，6 months / -20°C，1 month ;
背景介绍 Sumatriptan-d is intended for use as an internal standard for the quantification of sumatriptan by GC- or LC-MS. Sumatriptan is an agonist of the serotonin (5-HT) receptor subtypes 5-HT and 5-HT (ICs = 9.3 and 7.3 nM, respectively). It also binds to the 5-HT receptor (IC = 17.8 nM). It induces vasoconstriction in isolated human middle meningeal arteries (EC = 89.9 nM), an effect that can be reduced by the 5-HT receptor antagonists GR125743 and GR127935 . Sumatriptan reduces acute, but not chronic, mechanical hyperalgesia in a mouse model of pain induced by nitroglycerin, which is a known migraine trigger in humans. Formulations containing sumatriptan have been used in the treatment of migraine headache.
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