(R)-Crizotinib-d5

产品编号 HY-14013
产品分类 抑制剂
CAS号 1395950-84-1
分子式 C21H17Cl2D5FN5O
分子量 455.37
品牌 华韵生物
规格 500μg 1mg
应用 (R)-Crizotinib-d is intended for use as an internal standard for the quantification of (R)-crizotinib by GC- or LC-MS. (R)-Crizotinib is a derivative of aminopyridine that acts as a potent, orally bioavailable, ATP-competitive small-molecule dual inhibitor of c-MET (IC = 8 nM) and ALK (IC = 20 nM) receptor tyrosine kinases. (R)-Crizotinib shows antitumor efficacy, including cytoreductive antitumor activity, in multiple tumor models implanted in athymic mice that express activated c-MET or ALK fusion proteins (ICs = 5-20 nM).
品牌 货号 纯度 规格 目录价(CNY) 会员价(CNY) 数量 购物车
华韵生物 HY-14013-500μg 500μg ¥16537.00
华韵生物 HY-14013-1mg 1mg ¥31421.00
COA查询 查询MSDS 大包装询盘
CAS号 1395950-84-1
分子式 C21H17Cl2D5FN5O
分子量 455.37
纯度 ≥99% deuterated forms (d1-d5)
状态 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至37℃，然后在超声波浴中震荡一段时间。
存储 Pure form：
-20°C，3 years / 4°C，2 years ;
In solvent：
-80°C，6 months / -20°C，1 month ;
背景介绍 (R)-Crizotinib-d is intended for use as an internal standard for the quantification of (R)-crizotinib by GC- or LC-MS. (R)-Crizotinib is a derivative of aminopyridine that acts as a potent, orally bioavailable, ATP-competitive small-molecule dual inhibitor of c-MET (IC = 8 nM) and ALK (IC = 20 nM) receptor tyrosine kinases. (R)-Crizotinib shows antitumor efficacy, including cytoreductive antitumor activity, in multiple tumor models implanted in athymic mice that express activated c-MET or ALK fusion proteins (ICs = 5-20 nM).
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