| 名称 |
PE/Cyanine7 Anti-Human CD62L Antibody[HI62L] |
| 来源 |
Mouse |
| 应用 |
FCM |
| 反应 |
Human |
| 克隆 |
HI62L |
| 状态 |
PE/Cyanine7 is designed to be excited by the Blue (488 nm), Green (532 nm) and yellow-green (561 nm) lasers and detected using an optical filter centered near 775 nm (e.g., a 780/60 nm bandpass filter). |
| 亚型 |
Mouse IgG2a, κ |
| 基因ID |
6402 |
| 存储 |
Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| 别名 |
CD62L;CD62 antigen-like family member L;L-selectin;LAM-1;LECAM1;Lnhr;Ly-22;Ly22;Lymph node homing receptor;Sell |
| 背景介绍 |
CD62L is a 74-95 kD single chain type I glycoprotein referred to as L-selectin or LECAM-1. It is expressed on most peripheral blood B cells, subsets of T and NK cells, monocytes, granulocytes, and certain hematopoietic malignant cells. CD62L binds to carbohydrates present on certain glycoforms of CD34, glycam-1, and MAdCAM-1 and with a low affinity to anionic oligosaccharide sequences related to sialylated Lewis X (sLex, CD15s) through its C-type lectin domain. CD62L is important for the homing of naïve lymphocytes to high endothelial venules in peripheral lymph nodes and Peyer's patches. It also plays a role in leukocyte rolling on activated endothelial cells. |
