| 名称 |
PE/Cyanine7 Anti-Mouse CD122/IL-2RB Antibody[5H4] |
| 来源 |
Rat |
| 应用 |
FCM |
| 反应 |
Mouse |
| 克隆 |
5H4 |
| 状态 |
PE/Cyanine7 is designed to be excited by the Blue (488 nm), Green (532 nm) and yellow-green (561 nm) lasers and detected using an optical filter centered near 775 nm (e.g., a 780/60 nm bandpass filter). |
| 亚型 |
Rat IgG2a, κ |
| 基因ID |
16185 |
| 存储 |
Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| 别名 |
IL-2R subunit beta;CD122;High affinity IL-2 receptor subunit beta;IL-2 receptor subunit beta;IL-2RB;Il2rb;Interleukin-2 receptor subunit beta;p70-75 |
| 背景介绍 |
CD122 is a 70-75 kD IL-2 receptor β chain also known as IL-2Rβ, which is also shared by the IL-15 receptor. It is constitutively expressed by NK cells and at lower levels by T cells, B cells, monocytes, and macrophages. The IL-2Rβ chain can combine with either the common γ subunit (γc, CD132) alone or with the γc subunit and the IL-2Rα subunit (CD25) to generate intermediate or high affinity IL-2 receptor complexes, respectively. CD122 expression levels can be upregulated by activation. The 5H4 antibody does not block IL-2 binding to the IL-2 receptor. CD122 is expressed on murine, but not human, CD8+ Tregs involved in the maintenance of T cell homeostasis. |
