6-Formylpterin

产品编号 HY-17699
产品分类 抑制剂
CAS号 712-30-1
分子式 C7H5N5O2
分子量 191.10
品牌 华韵生物
规格 500μg 1mg 5mg 10mg
应用 Xanthine oxidase (XO) generates reactive oxygen species, including hydrogen peroxide (HO), as it oxidizes specific substrates in the presence of water and oxygen. 6-Formylpterin is an oxidized pterin produced by photolytic breakdown of folic acid. It binds to one of two active sites on XO nearly quantitatively and irreversibly and prevents the metabolism of other substrates at the second site, resulting in “hetero-substrate” inhibition at nanomolar concentrations. However, 6-formylpterin itself is converted by XO to 6-carboxylpterin and HO and the turnover rate of this reaction can actually be accelerated by prior binding of a hetero-substrate to XO. In this way, 6-formylpterin acts as an intracellular generator of HO in cells expressing XO, altering cellular function.
品牌 货号 纯度 规格 目录价(CNY) 会员价(CNY) 数量 购物车
华韵生物 HY-17699-500μg 500μg ¥5118.00
华韵生物 HY-17699-1mg 1mg ¥9765.00
华韵生物 HY-17699-5mg 5mg ¥40950.00
华韵生物 HY-17699-10mg 10mg ¥66543.00
CAS号 712-30-1
分子式 C7H5N5O2
分子量 191.10
纯度 ≥98%
状态 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。
储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
为了提高溶解度,请将管子加热至37℃,然后在超声波浴中震荡一段时间。
存储 Pure form:
-20°C,3 years / 4°C,2 years ;
In solvent:
-80°C,6 months / -20°C,1 month ;
背景介绍 Xanthine oxidase (XO) generates reactive oxygen species, including hydrogen peroxide (HO), as it oxidizes specific substrates in the presence of water and oxygen. 6-Formylpterin is an oxidized pterin produced by photolytic breakdown of folic acid. It binds to one of two active sites on XO nearly quantitatively and irreversibly and prevents the metabolism of other substrates at the second site, resulting in “hetero-substrate” inhibition at nanomolar concentrations. However, 6-formylpterin itself is converted by XO to 6-carboxylpterin and HO and the turnover rate of this reaction can actually be accelerated by prior binding of a hetero-substrate to XO. In this way, 6-formylpterin acts as an intracellular generator of HO in cells expressing XO, altering cellular function.
暂无相关论文!
说明书更新中,请联系业务员索取!
暂无技术文章!
象形图
警示语
Class
警告声明
UNub
危险声明
Packing Group
搜索质检报告(COA)
相关产品